The user can access the application through a web interface, in combination with the GenoList environment, thus taking advantage of comparative genome data. Alternatively, a stand-alone client is available (multi-platform AIR), allowing the user to work with its own locally stored data. Currently, the accepted file formats are ptt (GenBank) for genome annotation, tab-delimited files for other information (protein correspondences, Single Nucleotide Polymorphisms – SNPs) and the Newick format for phylogenetic trees. Web access can also be implemented using local user flat files.